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Blow fill seals free from errors Whether infusion bottles or ampoule strips: newly developed HEUFT spotter II BFS systems are proving their worth during the all-around inspection of aseptically produced blow fill seal containers filled with sterile pharmaceutical liquid dosages.
Large volume parenterals (LVPs) such as saline, electrolyte and glucose solutions or even inhalation products, eye drops and other small volume parenterals (SVPs): sensitive preparations such as these are preferably administered from blow fill seal bottles and ampoules made of polypropylene or polyethylene. They are aseptically manufactured and considered to be superior primary packaging for such applications – provided that they are free from defects, deformations or cosmetic faults, correctly filled and hermetically sealed. New HEUFT spotter II BFS devices check this along an efficient linear system. They achieve full coverage and precision during the in-line inspection of such primary packaging with smart lighting, optomechanics, image filtering and subtraction as well as image evaluation adapted to different fault categories. They are subjected to 100% integrity testing as required by the Good Manufacturing Practice ( GMP). For this every single blow fill seal container is inspected all around from the closure to the base in order to find deformations, missing or excess packaging components, contamination, scratches, grooves, inclusions and cosmetic defects in the container material just as safely as foreign particles inside it. Deviations in the filling quantity and the colour of the liquid parenterals inside are also detected reliably.
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