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[药品研发] RECIST — learning from the past to build the future

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发表于 2016-12-21 10:08:04 | 显示全部楼层 |阅读模式

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Response Evaluation Criteria In Solid Tumours (RECIST) remain an integral part of the assessment of tumour burden in many clinical trials in oncology; these criteria are used to evaluate the activity and efficacy of new cancer therapeutics in solid tumours. We aim to define the purpose of RECIST, and reflect on the level of documentation needed to enable changes for these criteria to  develop a new RECIST. Maintaining the applicability of RECIST as a standard evaluation approach is associated with many challenges, in particular with maintaining a balance between the specificity and generalizability, continued validation and innovation, and use of RECIST in early phase versus late-phase drug development, as well as its relevance in clinical trials versus clinical practice. Key questions relate to different modes of actions of new classes of treatments and new imaging modalities; thus, the RECIST Working Group remains committed to maintain RECIST as a standard for the oncology community.




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 楼主| 发表于 2016-12-21 10:13:11 | 显示全部楼层
如果有志于研究实体肿瘤的疗效评价标准(Response Evaluation Criteria In Solid Tumours (RECIST))可以留下联系方式,我有两篇关于该该主题的文献《RECIST — learning from the past to build the future》和《New response evaluation criteria in solid tumours Revised RECIST guideline (version 1.1)》
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药士
发表于 2016-12-21 10:29:06 | 显示全部楼层
考验我能力的事情,我不干
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药徒
发表于 2016-12-21 12:04:16 | 显示全部楼层
这意思就是有偿服务呗
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